Abstract

Research Article

Factors Influencing Knowledge on the Completion of Treatment among Tuberculosis Patients under Directly Observed Treatment Strategy (DOTS) in a Selected Health Facility, the Bahamas

Esther S Daniel*, Latasha Collie, Alice Neymour, Nicole KA Martin-Chen, Kevin Moss, Kathy-Ann Lootawan and Virginia M Victor

Published: 25 March, 2024 | Volume 8 - Issue 1 | Pages: 022-030

Objective: To determine the factors influencing completion of DOTS in Tuberculosis treatment in the Bahamas.
Methods: A quantitative, descriptive cross-sectional survey. Tuberculosis patients aged 18 years and above were considered regardless of the site or the smear status of their TB. The sample size 
was 40. Data analysis and interpretation were done using the statistical package for the social sciences software (SPSS version 24), through the exploration and calculation of descriptive (frequencies, percentages, means, standard deviations, and inferential (Anova) statistical methods. Statistical significance was determined to be a p < 0.05. 
Results: The mean age of the respondents, was 39.9 years, SD 11.65, and 73% of them were men. 63% of participants, 78% of whom were citizens of the Bahamas, reported having no annual income. Seventy-eight percent (31) of the participants said they had insufficient food and drink while they were unwell. More than half of the participants in the survey reported being on at least one pharmaceutical regimen, although 36% said they were not actively taking any of the prescription medications.
Conclusion: Less than a third were noncompliant with DOTS, this was influenced by factors such as annual income, no family support, marital status, employment status, and educational level.

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001053 Cite this Article Read Full Article PDF

Keywords:

Tuberculosis; DOTS; Adherence; Knowledge; Influencing factors

References

  1. Tuberculosis (TB). World Health Organization.2024 Mar 20. https://www.who.int/news-room/fact-sheets/detail/tuberculosis
  2. Ministry of Health. Tuberculosis (TB) Control. Nassau: Ministry of Health; n.d. 2020 Feb 29. https://www.bahamas.gov.bs/wps/portal/public/HealthInitiatives/Tuberculosis control
  3. World Health Organization (WHO) 2016a Global Tuberculosis report. 2016 Geneva. WHO Bloom BR. Tuberculosis. Major Infectious Diseases. 3rd edition. U.S. National Library of Medicine; 2017 [cited 2020 Feb 22]. https://www.ncbi.nlm.gov/books/NBK525174
  4. HIV and Tuberculosis (TB) Understanding HIV/AIDS. National Institutes of Health. U.S. Department of Health and Human Services; 2019 [cited 2020Feb 11]. https://aidsinfo.nih.gov/understanding-hiv-aids/fact-sheets/26/90/hiv-and-tuberculosis--tb-/
  5. Seung KJ, Keshavjee S, Rich ML. Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis. Cold Spring Harb Perspect Med. 2015 Apr 27;5(9):a017863. doi: 10.1101/cshperspect.a017863. PMID: 25918181; PMCID: PMC4561400.
  6. Substance Abuse and Mental Health Services Administration (US). Health Care Systems and Substance Use Disorders. Facing Addiction in America: The Surgeon General's Report on Alcohol, Drugs, and Health. U.S. National Library of Medicine; [cited 2020, Mar 20]. https://www.ncbi.nlm.nih.gov/books/NBK424848/
  7. Yao X, Liu Y, Liu Y, Liu W, Ye Z, Zheng C, Ge S. Multiplex analysis of plasma cytokines/chemokines showing different immune responses in active TB patients, latent TB infection and healthy participants. Tuberculosis (Edinb). 2017 Dec; 107:88-94. doi: 10.1016/j.tube.2017.07.013. Epub 2017 Aug 3. PMID: 29050777.
  8. Herrero MB, Ramos S, Arrossi S. Determinants of non adherence to tuberculosis treatment in Argentina: barriers related to access to treatment. Rev Bras Epidemiol. 2015 Apr-Jun;18(2):287-98. doi: 10.1590/1980-5497201500020001. PMID: 26083503.
  9. Mwanza J. Sickrole Compliance and Sickrole Deviance among Tuberculosis Patients on Treatment in Kanyama, a Zambian Shanty Compound. Adv. Appl. Sociol. 2016 [cited 2020 Mar 15];6(01). https://www.scirp.org/journal/paperinformation.aspx?paperid=62834
  10. Kaona FA, Tuba M, Siziya S, Sikaona L. An assessment of factors contributing to treatment adherence and knowledge of TB transmission among patients on TB treatment. BMC Public Health. 2004 Dec 29;4:68. doi: 10.1186/1471-2458-4-68. PMID: 15625004; PMCID: PMC545081.
  11. Sanneh AF, Pollock JI. Comparison of Pulmonary TB DOTS clinic medication before and after the introduction of daily DOTS treatment and attitudes of treatment defaulters in the Western Division of the Gambia. Afr Health Sci. 2010 Jun;10(2):165-71. PMID: 21326970; PMCID: PMC2956295.
  12. Bam TS, Gunneberg C, Chamroonsawasdi K, Bam DS, Aalberg O, Kasland O, Shiyalap K, Srisorrachatr S. Factors affecting patient adherence to DOTS in urban Kathmandu, Nepal. Int J Tuberc Lung Dis. 2006 Mar;10(3):270-6. PMID: 16562706.
  13. Mushtaq MU, Shahid U, Abdullah HM, Saeed A, Omer F, Shad MA, Siddiqui AM, Akram J. Urban-rural inequities in knowledge, attitudes and practices regarding tuberculosis in two districts of Pakistan's Punjab province. Int J Equity Health. 2011 Feb 4;10:8. doi: 10.1186/1475-9276-10-8. PMID: 21294873; PMCID: PMC3045313.
  14. Wang J, Fei Y, Shen H, Xu B. Gender difference in knowledge of tuberculosis and associated health-care seeking behaviors: a cross-sectional study in a rural area of China. BMC Public Health. 2008 Oct 8;8:354. doi: 10.1186/1471-2458-8-354. PMID: 18842127; PMCID: PMC2577657.
  15. McIntosh J, Forbes N, Moss K, Frankson MA. 1373. Clinical Presentation, Demographics, and Outcomes of Cases of Tuberculosis (TB) at Princess Margaret Hospital, Nassau, The Bahamas 2014–2016. In Open Forum Infectious Diseases 2019 Oct (Vol. 6, No. Suppl 2, p. S498). Oxford University Press.
  16. Reumers L, Bekker M, Hilderink H, Jansen M, Helderman JK, Ruwaard D. Qualitative modelling of social determinants of health using group model building: the case of debt, poverty, and health. Int J Equity Health. 2022 May 19;21(1):72. doi: 10.1186/s12939-022-01676-7. PMID: 35590354; PMCID: PMC9118602.
  17. Nedjat S, Mehrdad R, Yunesian M, Pouragha H, Biagi V, Monazzam-Esmaeelpour MR. Prospective cohort study on the social determinants of health: Tehran University of Medical Sciences employees` cohort (TEC) study protocol. BMC Public Health. 2020 Nov 13;20(1):1703. doi: 10.1186/s12889-020-09798-9. PMID: 33187513; PMCID: PMC7666496.
  18. World Health Organization (WHO). Global tuberculosis report. Geneva, Switzerland: World Health Organization. 2019.
  19. Tola HH, Tol A, Shojaeizadeh D, Garmaroudi G. Tuberculosis Treatment Non-Adherence and Lost to Follow Up among TB Patients with or without HIV in Developing Countries: A Systematic Review. Iran J Public Health. 2015 Jan;44(1):1-11. PMID: 26060770; PMCID: PMC4449995.
  20. Adjemian J, Frankland TB, Daida YG, Honda JR, Olivier KN, Zelazny A, Honda S, Prevots DR. Epidemiology of Nontuberculous Mycobacterial Lung Disease and Tuberculosis, Hawaii, USA. Emerg Infect Dis. 2017 Mar;23(3):439-447. doi: 10.3201/eid2303.161827. PMID: 28221128; PMCID: PMC5382761.
  21. Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG. Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance. BMC Med. 2016 Mar 23;14:31. doi: 10.1186/s12916-016-0575-9. PMID: 27005572; PMCID: PMC4804620.
  22. Bloom BR, Atun R, Cohen T, Dye C, Fraser H, Gomez GB, et al. Chapter 11 Tuberculosis. In Holmes KK, Bertozzi S, Bloom BR, editors. Major infectious diseases. 3rd ed. Washington, DC: The World Bank; 2017 [cited 2020 Feb 22]. Chapter 11. https://www.ncbi.nlm.nih.gov/books/NBK525174/

Figures:

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More

Help ?